Gene Information
Gene NameBAZ1B
OrganismHomo sapiens (Human)
Gene Length1483
Protein NamesTyrosine-protein kinase BAZ1B (EC 2.7.10.2) (Bromodomain adjacent to zinc finger domain protein 1B) (Williams syndrome transcription factor) (Williams-Beuren syndrome chromosomal region 10 protein) (Williams-Beuren syndrome chromosomal region 9 protein) (hWALp2)
Target NameNA
Target TypeNA
Gene Age950 ( ENSG00000009954 )
Evolutionary StageOpisthokonta
AlphaFoldDBQ9UIG0
Gene CardBAZ1B
Uniprot IDQ9UIG0
PfamPF00439; PF00628; PF10537; PF15612; PF15613
In ASDno
Allosteric Predictionyes (0.321892929)
Ortholog in AnimalsAlpaca_ BAZ1B ( ortholog_one2one )
Dog_ BAZ1B ( ortholog_one2one )
GuineaPig_ BAZ1B ( ortholog_one2one )
Macaque_ BAZ1B ( ortholog_one2one )
Mouse_ Baz1b ( ortholog_one2one )
Pig_ BAZ1B ( ortholog_one2one )
Rat_ Baz1b ( ortholog_one2one )
Rabbit_ BAZ1B ( ortholog_one2one )
OhnologsNA
ParalogsBAZ1A, BRD4, BRDT, KAT2A, CECR2, BAZ2A, BRD3, BRD2, BAZ2B, KAT2B, BPTF
TissueNA
Tissue SpecificityUbiquitously expressed with high levels of expression in heart, brain, placenta, skeletal muscle and ovary.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1F62  (NMR  -  )  5NNF  (X-ray  1.15A  ) 
DBSNP NA 
Subcellular location [CC]Nucleus {ECO:0000255|PROSITE-ProRule:PRU00063, ECO:0000255|PROSITE-ProRule:PRU00475, ECO:0000269|PubMed:11980720, ECO:0000269|PubMed:15543136, ECO:0000269|PubMed:16603771}. Note=Accumulates in pericentromeric heterochromatin during replication. Co-localizes with PCNA at replication foci during S phase (PubMed:15543136). Co-localizes with SMARCA5/SNF2H at replication foci during late-S phase (PubMed:15543136). Also localizes to replication foci independently of SMARCA5/SNF2H and PCNA (PubMed:15543136). {ECO:0000269|PubMed:15543136}.
Mouse PG classificationNA
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