| Gene Information | |
|---|---|
| Gene Name | PABPC4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 644 |
| Protein Names | Polyadenylate-binding protein 4 (PABP-4) (Poly(A)-binding protein 4) (Activated-platelet protein 1) (APP-1) (Inducible poly(A)-binding protein) (iPABP) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000090621 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q13310 |
| Gene Card | PABPC4 |
| Uniprot ID | Q13310 |
| Pfam | PF00658; PF00076 |
| In ASD | no |
| Allosteric Prediction | yes (0.133994836) |
| Ortholog in Animals | Alpaca_ PABPC4 ( ortholog_one2one ) Dog_ PABPC4 ( ortholog_one2one ) GuineaPig_ PABPC4 ( ortholog_one2one ) Macaque_ PABPC4 ( ortholog_one2one ) Mouse_ Pabpc4 ( ortholog_one2one ) Pig_ PABPC4 ( ortholog_one2one ) Rat_ Pabpc4 ( ortholog_one2many ) Rabbit_ PABPC4 ( ortholog_one2one ) |
| Ohnologs | PABPC1, PABPC1L, PABPC3 |
| Paralogs | RBMS2, PABPC1, PABPC3, RBM24, ELAVL4, ELAVL3, RBMS1, ELAVL2, PUF60, RBM34, RBM45, HNRNPR, SYNCRIP, PABPC1L, PABPC5, RBM14, PABPC1L2A, PABPC1L2B, SF3B4, RBM38, ELAVL1, TARDBP, RBMS3, PABPC4L |
| Tissue | NA |
| Tissue Specificity | Expressed at low levels in resting normal T cells; following T-cell activation, however, mRNA levels are rapidly up-regulated. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.009302(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs9820 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:17289661}. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. |
| Mouse PG classification | NA |
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