| Gene Information | |
|---|---|
| Gene Name | FDX2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 186 |
| Protein Names | Ferredoxin-2, mitochondrial (Adrenodoxin-like protein) (Ferredoxin-1-like protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000267673 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q6P4F2 |
| Gene Card | FDX2 |
| Uniprot ID | Q6P4F2 |
| Pfam | PF00111 |
| In ASD | no |
| Allosteric Prediction | no (-0.435564751) |
| Ortholog in Animals | Alpaca_ FDX2 ( ortholog_one2one ) Dog_ FDX2 ( ortholog_one2one ) GuineaPig_ FDX2 ( ortholog_one2one ) Macaque_ FDX2 ( ortholog_one2one ) Mouse_ Fdx2 ( ortholog_one2one ) Pig_ FDX2 ( ortholog_one2one ) Rat_ Fdx2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | FDX1 |
| Tissue | NA |
| Tissue Specificity | Widely expressed, with highest levels in testis, kidney and brain (at protein level) (PubMed:20547883). Expressed in muscle (at protein level) (PubMed:24281368, PubMed:30010796). Expressed in fibroblasts (at protein level) (PubMed:24281368). {ECO:0000269|PubMed:20547883, ECO:0000269|PubMed:24281368, ECO:0000269|PubMed:30010796}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2Y5C (X-ray 1.70A ) |
| DBSNP | rs587777600 rs888630930 |
| Subcellular location [CC] | Mitochondrion {ECO:0000269|PubMed:20547883, ECO:0000269|PubMed:24281368}. Mitochondrion matrix {ECO:0000250|UniProtKB:P10109}. |
| Mouse PG classification | NA |
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