| Gene Information | |
|---|---|
| Gene Name | BARK1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 689 |
| Protein Names | Beta-adrenergic receptor kinase 1 (Beta-ARK-1) (EC 2.7.11.15) (G-protein coupled receptor kinase 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P25098 |
| Gene Card | GRK2 |
| Uniprot ID | P25098 |
| Pfam | PF00169; PF00069; PF00615 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in peripheral blood leukocytes. {ECO:0000269|PubMed:10085131}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001823(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1BAK (NMR - ) 3CIK (X-ray 2.75A ) 3KRW (X-ray 2.90A ) 3KRX (X-ray 3.10A ) 3V5W (X-ray 2.07A ) 4MK0 (X-ray 2.40A ) 4PNK (X-ray 2.56A ) 5HE1 (X-ray 3.15A ) 5UKK (X-ray 2.60A ) 5UKL (X-ray 2.15A ) 5UUU (X-ray 2.70A ) 5UVC (X-ray 2.65A ) 5WG3 (X-ray 2.90A ) 5WG4 (X-ray 2.31A ) 5WG5 (X-ray 3.10A ) 6C2Y (X-ray 2.74A ) 6U7C (X-ray 2.44A ) 7K7L (X-ray 2.54A ) 7K7Z (X-ray 2.61A ) 7PWD (X-ray 2.60A ) |
| DBSNP | rs55696045 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250|UniProtKB:P26817}. Cell membrane {ECO:0000250|UniProtKB:P21146}. Postsynapse {ECO:0000250|UniProtKB:P26817}. Presynapse {ECO:0000250|UniProtKB:P26817}. |
| Mouse PG classification | NA |
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