| Gene Information | |
|---|---|
| Gene Name | BANK1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 785 |
| Protein Names | B-cell scaffold protein with ankyrin repeats |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000153064 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8NDB2 |
| Gene Card | BANK1 |
| Uniprot ID | Q8NDB2 |
| Pfam | PF14545; PF18567 |
| In ASD | no |
| Allosteric Prediction | no (-0.358379755) |
| Ortholog in Animals | Alpaca_ BANK1 ( ortholog_one2one ) Dog_ BANK1 ( ortholog_one2one ) Macaque_ BANK1 ( ortholog_one2one ) Mouse_ Bank1 ( ortholog_one2one ) Pig_ BANK1 ( ortholog_one2one ) Rat_ Bank1 ( ortholog_one2one ) Rabbit_ BANK1 ( ortholog_one2one ) |
| Ohnologs | PIK3AP1 |
| Paralogs | PIK3AP1 |
| Tissue | spleen |
| Tissue Specificity | Expressed in B-cell but not T-cell or myeloid cell lines. Highest expression in CD19(+) B-cells, with very low expression in other cell populations. {ECO:0000269|PubMed:11782428, ECO:0000269|PubMed:18204447}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.088150(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs10516487 rs3733197 rs3113676 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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