| Gene Information | |
|---|---|
| Gene Name | BAL2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1801 |
| Protein Names | Protein mono-ADP-ribosyltransferase PARP14 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (B aggressive lymphoma protein 2) (Poly [ADP-ribose] polymerase 14) (PARP-14) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q460N5 |
| Gene Card | PARP14 |
| Uniprot ID | Q460N5 |
| Pfam | PF01661; PF00644 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in macrophages. {ECO:0000269|PubMed:27796300}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3GOY (X-ray 2.80A ) 3Q6Z (X-ray 2.23A ) 3Q71 (X-ray 2.20A ) 3SE2 (X-ray 2.30A ) 3SMI (X-ray 2.40A ) 3SMJ (X-ray 1.50A ) 3VFQ (X-ray 2.80A ) 4ABK (X-ray 1.60A ) 4ABL (X-ray 1.15A ) 4D86 (X-ray 2.00A ) 4F1L (X-ray 1.90A ) 4F1Q (X-ray 2.80A ) 4PY4 (X-ray 2.76A ) 5LXP (X-ray 2.07A ) 5LYH (X-ray 2.17A ) 5NQE (X-ray 2.71A ) 5O2D (X-ray 1.60A ) 5QHT (X-ray 1.05A ) 5QHU (X-ray 1.05A ) 5QHV (X-ray 1.05A ) 5QHW (X-ray 1.12A ) 5QHX (X-ray 1.11A ) 5QHY (X-ray 1.17A ) 5QHZ (X-ray 1.15A ) 5QI0 (X-ray 1.05A ) 5QI1 (X-ray 1.05A ) 5QI2 (X-ray 1.08A ) 5QI3 (X-ray 1.05A ) 5QI4 (X-ray 1.20A ) 5QI5 (X-ray 1.05A ) 5QI6 (X-ray 1.10A ) 5QI7 (X-ray 1.05A ) 5QI8 (X-ray 1.09A ) 5QI9 (X-ray 1.05A ) 5QIA (X-ray 1.14A ) 5V7T (X-ray 2.30A ) 5V7W (X-ray 2.65A ) 6FYM (X-ray 2.15A ) 6FZM (X-ray 2.67A ) 6G0W (X-ray 2.34A ) 6WE2 (X-ray 2.66A ) 6WE3 (X-ray 1.95A ) 6WE4 (X-ray 1.60A ) 7D2C (X-ray 1.56A ) 7L9Y (X-ray 2.25A ) 7LUN (X-ray 2.57A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000250|UniProtKB:Q2EMV9}. Cytoplasm {ECO:0000269|PubMed:27796300}. Note=In steady state splenocytes the protein is mostly nuclear (By similarity). A minor proportion is detected in the cytoplasm (By similarity). In macrophages, mainly localizes to the cytoplasm (PubMed:27796300). {ECO:0000250|UniProtKB:Q2EMV9, ECO:0000269|PubMed:27796300}. |
| Mouse PG classification | NA |
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