| Gene Information | |
|---|---|
| Gene Name | BAK |
| Organism | Homo sapiens (Human) |
| Gene Length | 211 |
| Protein Names | Bcl-2 homologous antagonist/killer (Apoptosis regulator BAK) (Bcl-2-like protein 7) (Bcl2-L-7) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q16611 |
| Gene Card | BAK1 |
| Uniprot ID | Q16611 |
| Pfam | PF00452 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in a wide variety of tissues, with highest levels in the heart and skeletal muscle. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002657(Rat);0.153411(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 1BXL (NMR - ) 2IMS (X-ray 1.48A ) 2IMT (X-ray 1.49A ) 2JBY (X-ray 2.41A ) 2JCN (X-ray 1.80A ) 2LP8 (NMR - ) 2M5B (NMR - ) 2XPX (X-ray 2.05A ) 2YV6 (X-ray 2.50A ) 3I1H (X-ray 2.20A ) 3QBR (X-ray 2.60A ) 4D2L (X-ray 2.90A ) 4U2U (X-ray 2.90A ) 4U2V (X-ray 2.30A ) 4UF1 (X-ray 2.30A ) 5AJK (X-ray 2.55A ) 5FMI (X-ray 1.49A ) 5FMK (X-ray 1.73A ) 5VWV (X-ray 1.90A ) 5VWW (X-ray 2.80A ) 5VWX (X-ray 2.49A ) 5VWY (X-ray 1.55A ) 5VWZ (X-ray 1.62A ) 5VX0 (X-ray 1.60A ) 5VX1 (X-ray 1.22A ) 6ODH (X-ray 2.30A ) 6UXM (X-ray 2.49A ) 6UXN (X-ray 2.49A ) 6UXO (X-ray 1.80A ) 6UXP (X-ray 2.49A ) 6UXQ (X-ray 1.70A ) 6UXR (X-ray 1.80A ) 7K02 (X-ray 3.40A ) 7LK4 (X-ray 3.10A ) 7M5A (X-ray 1.50A ) 7M5B (X-ray 1.85A ) 7OFM (NMR - ) 7OFO (NMR - ) |
| DBSNP | rs4987115 rs1051911 rs5745592 |
| Subcellular location [CC] | Mitochondrion outer membrane {ECO:0000269|PubMed:29531808}; Single-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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