| Gene Information | |
|---|---|
| Gene Name | ADGRA3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1321 |
| Protein Names | Adhesion G protein-coupled receptor A3 (G-protein coupled receptor 125) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000152990 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8IWK6 |
| Gene Card | ADGRA3 |
| Uniprot ID | Q8IWK6 |
| Pfam | PF00002; PF01825; PF07679; PF13855 |
| In ASD | no |
| Allosteric Prediction | no (-0.62650129) |
| Ortholog in Animals | Alpaca_ ADGRA3 ( ortholog_one2one ) Dog_ ADGRA3 ( ortholog_one2one ) GuineaPig_ ADGRA3 ( ortholog_one2one ) Macaque_ ADGRA3 ( ortholog_one2one ) Mouse_ Adgra3 ( ortholog_one2one ) Pig_ ADGRA3 ( ortholog_one2one ) Rat_ Adgra3 ( ortholog_one2one ) |
| Ohnologs | ADGRA2, ADGRA1 |
| Paralogs | ADGRE3, ADGRL2, VIPR1, ADGRL4, ADGRE2, ADGRG4, ADGRD1, ADGRL3, GHRHR, PTH2R, ADGRE1, ADGRD2, ADGRL1, ADGRB3, EVA1C, ADGRG1, SCTR, ADGRF5, GLP2R, PTH1R, CALCR, ADGRF3, GIPR, ADGRA1, ADGRF1, ADCYAP1R1, ADGRG5, ADGRE5, CRHR2, ADGRB2, ADGRG6, GCGR, ADGRB1, ADGRG2, ADGRA2, ADGRF4, VIPR2, ADGRG7, CALCRL, ADGRG3, CRHR1, GLP1R |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs9002 rs3814416 |
| Subcellular location [CC] | Membrane {ECO:0000250|UniProtKB:S4X0Q8}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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