| Gene Information | |
|---|---|
| Gene Name | BAD |
| Organism | Homo sapiens (Human) |
| Gene Length | 168 |
| Protein Names | Bcl2-associated agonist of cell death (BAD) (Bcl-2-binding component 6) (Bcl-2-like protein 8) (Bcl2-L-8) (Bcl-xL/Bcl-2-associated death promoter) (Bcl2 antagonist of cell death) |
| Target Name | bcl2 antagonist of cell death |
| Target Type | NA |
| Gene Age | 168 ( ENSG00000002330 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q92934 |
| Gene Card | BAD |
| Uniprot ID | Q92934 |
| Pfam | PF10514 |
| In ASD | no |
| Allosteric Prediction | yes (0.839060198) |
| Ortholog in Animals | Alpaca_ BAD ( ortholog_one2one ) Dog_ BAD ( ortholog_one2one ) Macaque_ BAD ( ortholog_one2one ) Mouse_ Bad ( ortholog_one2one ) Pig_ BAD ( ortholog_one2one ) Rat_ Bad ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in a wide variety of tissues. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1G5J (NMR - ) 7Q16 (X-ray 2.36A ) |
| DBSNP | rs3729933 |
| Subcellular location [CC] | Mitochondrion outer membrane. Cytoplasm {ECO:0000250|UniProtKB:Q61337}. Note=Colocalizes with HIF3A in the cytoplasm (By similarity). Upon phosphorylation, locates to the cytoplasm. {ECO:0000250|UniProtKB:Q61337}. |
| Mouse PG classification | NA |
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