| Gene Information | |
|---|---|
| Gene Name | BACH2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 841 |
| Protein Names | Transcription regulator protein BACH2 (BTB and CNC homolog 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000112182 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9BYV9 |
| Gene Card | BACH2 |
| Uniprot ID | Q9BYV9 |
| Pfam | PF00651; PF03131 |
| In ASD | no |
| Allosteric Prediction | no (-1.004576306) |
| Ortholog in Animals | Alpaca_ BACH2 ( ortholog_one2one ) Dog_ BACH2 ( ortholog_one2one ) GuineaPig_ BACH2 ( ortholog_one2one ) Macaque_ BACH2 ( ortholog_one2one ) Mouse_ Bach2 ( ortholog_one2one ) Pig_ BACH2 ( ortholog_one2one ) Rat_ Bach2 ( ortholog_one2one ) Rabbit_ BACH2 ( ortholog_one2one ) |
| Ohnologs | BACH1 |
| Paralogs | KLHL40, KLHDC7B, GAN, BACH1, KLHL20, KLHL10, KLHL42, KLHL21, KLHL32, KBTBD7, KBTBD6, KLHL30, KLHL15, KLHL38, KLHL41, KLHL26, KLHL17, KBTBD3, KLHL13, KLHL9, KLHL18, KLHL23, KLHDC7A, KLHL31, IVNS1ABP, KLHL1, KEAP1, KLHL8, KLHL2, KLHL29, KBTBD12, KLHL34, KLHL7, KLHL33, KLHL36, KLHL28, KBTBD11, KLHL14, CCIN, BTBD18, IPP, KLHDC8B, KLHL6, KLHL24, KLHL5, KBTBD13, KBTBD8, KLHL3, KLHL35, KLHL22, KBTBD2, KLHL12, KLHL4, KLHDC8A |
| Tissue | lymph.node, tonsil |
| Tissue Specificity | B-cell specific. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3OHU (X-ray 2.10A ) 3OHV (X-ray 2.20A ) |
| DBSNP | rs34335140 rs757652995 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:17018862, ECO:0000269|PubMed:28530713}. Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978, ECO:0000269|PubMed:17018862, ECO:0000269|PubMed:28530713}. Note=Nucleocytoplasmic shuttling is controlled by phosphorylation. {ECO:0000269|PubMed:17018862}. |
| Mouse PG classification | NA |
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