| Gene Information | |
|---|---|
| Gene Name | BABAM1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 329 |
| Protein Names | BRISC and BRCA1-A complex member 1 (Mediator of RAP80 interactions and targeting subunit of 40 kDa) (New component of the BRCA1-A complex) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000105393 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9NWV8 |
| Gene Card | BABAM1 |
| Uniprot ID | Q9NWV8 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.055683746) |
| Ortholog in Animals | Alpaca_ BABAM1 ( ortholog_one2one ) Dog_ BABAM1 ( ortholog_one2one ) GuineaPig_ BABAM1 ( ortholog_one2one ) Macaque_ BABAM1 ( ortholog_one2one ) Mouse_ Babam1 ( ortholog_one2one ) Pig_ BABAM1 ( ortholog_one2one ) Rat_ Babam1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.023334(Mouse);0.019922(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6H3C (EM 3.90A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:19261749, ECO:0000269|PubMed:24075985}. Nucleus {ECO:0000269|PubMed:19261746, ECO:0000269|PubMed:19261748, ECO:0000269|PubMed:19261749, ECO:0000269|PubMed:21282113, ECO:0000269|PubMed:24075985}. Note=Localizes at sites of DNA damage at double-strand breaks (DSBs). {ECO:0000269|PubMed:19261746, ECO:0000269|PubMed:19261748, ECO:0000269|PubMed:19261749, ECO:0000269|PubMed:21282113}. |
| Mouse PG classification | NA |
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