| Gene Information | |
|---|---|
| Gene Name | RALGAPA1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 2036 |
| Protein Names | Ral GTPase-activating protein subunit alpha-1 (GAP-related-interacting partner to E12) (GRIPE) (GTPase-activating Rap/Ran-GAP domain-like 1) (Tuberin-like protein 1) (p240) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000174373 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q6GYQ0 |
| Gene Card | RALGAPA1 |
| Uniprot ID | Q6GYQ0 |
| Pfam | PF20412; PF02145 |
| In ASD | no |
| Allosteric Prediction | no (-1.107480902) |
| Ortholog in Animals | Alpaca_ RALGAPA1 ( ortholog_one2one ) Dog_ RALGAPA1 ( ortholog_one2one ) GuineaPig_ RALGAPA1 ( ortholog_one2one ) Macaque_ RALGAPA1 ( ortholog_one2one ) Mouse_ Ralgapa1 ( ortholog_one2one ) Pig_ RALGAPA1 ( ortholog_one2one ) Rat_ Ralgapa1 ( ortholog_one2one ) Rabbit_ RALGAPA1 ( ortholog_one2one ) |
| Ohnologs | RALGAPA2 |
| Paralogs | RALGAPA2, TSC2 |
| Tissue | NA |
| Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:15498464}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2274068 rs1595085511 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Translocated to the nucleus, when associated with TCF3/E12. {ECO:0000250}. |
| Mouse PG classification | NA |
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