| Gene Information | |
|---|---|
| Gene Name | B4GALT5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 388 |
| Protein Names | Beta-1,4-galactosyltransferase 5 (Beta-1,4-GalTase 5) (Beta4Gal-T5) (b4Gal-T5) (EC 2.4.1.-) (Beta-1,4-GalT II) (Glucosylceramide beta-1,4-galactosyltransferase) (EC 2.4.1.274) (Lactosylceramide synthase) (LacCer synthase) (UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 5) (UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 5) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000158470 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O43286 |
| Gene Card | B4GALT5 |
| Uniprot ID | O43286 |
| Pfam | PF02709; PF13733 |
| In ASD | no |
| Allosteric Prediction | no (-1.028407989) |
| Ortholog in Animals | Alpaca_ B4GALT5 ( ortholog_one2one ) Dog_ B4GALT5 ( ortholog_one2one ) GuineaPig_ B4GALT5 ( ortholog_one2one ) Macaque_ B4GALT5 ( ortholog_one2one ) Mouse_ B4galt5 ( ortholog_one2one ) Pig_ B4GALT5 ( ortholog_one2one ) Rat_ B4galt5 ( ortholog_one2one ) Rabbit_ B4GALT5 ( ortholog_one2one ) |
| Ohnologs | B4GALT2, B4GALT6 |
| Paralogs | B4GALT4, B4GALT3, B4GALT1, B4GALT6, B4GALT2, B4GALT7 |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:9435216}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2273086 rs235035 rs35195217 |
| Subcellular location [CC] | Golgi apparatus, Golgi stack membrane {ECO:0000250|UniProtKB:P15291}; Single-pass type II membrane protein. Golgi apparatus {ECO:0000250|UniProtKB:A0A1S6M251}. Note=Trans cisternae of Golgi stack. {ECO:0000250|UniProtKB:P15291}. |
| Mouse PG classification | NA |
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