| Gene Information | |
|---|---|
| Gene Name | B4GALT2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 372 |
| Protein Names | Beta-1,4-galactosyltransferase 2 (Beta-1,4-GalTase 2) (Beta4Gal-T2) (b4Gal-T2) (EC 2.4.1.-) (Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase) (Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase) (EC 2.4.1.38) (Lactose synthase A protein) (EC 2.4.1.22) (N-acetyllactosamine synthase) (EC 2.4.1.90) (Nal synthase) (UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 2) (UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000117411 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O60909 |
| Gene Card | B4GALT2 |
| Uniprot ID | O60909 |
| Pfam | PF02709; PF13733 |
| In ASD | no |
| Allosteric Prediction | no (-1.108934959) |
| Ortholog in Animals | Alpaca_ B4GALT2 ( ortholog_one2one ) Dog_ B4GALT2 ( ortholog_one2one ) GuineaPig_ B4GALT2 ( ortholog_one2one ) Macaque_ B4GALT2 ( ortholog_one2one ) Mouse_ B4galt2 ( ortholog_one2one ) Pig_ B4GALT2 ( ortholog_one2one ) Rat_ B4galt2 ( ortholog_one2one ) Rabbit_ B4GALT2 ( ortholog_one2one ) |
| Ohnologs | B4GALT1, B4GALT4, B4GALT5 |
| Paralogs | B4GALT5, B4GALT4, B4GALT3, B4GALT1, B4GALT6, B4GALT7 |
| Tissue | NA |
| Tissue Specificity | Weakly expressed in various tissues. Highest expression in prostate, testis, ovary, intestine, muscle, and in fetal brain. {ECO:0000269|PubMed:9405390}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs1859728 rs35904809 |
| Subcellular location [CC] | Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Trans cisternae of Golgi stack. |
| Mouse PG classification | NA |
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