| Gene Information | |
|---|---|
| Gene Name | B4GALNT4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1039 |
| Protein Names | N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000182272 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q76KP1 |
| Gene Card | B4GALNT4 |
| Uniprot ID | Q76KP1 |
| Pfam | PF05679 |
| In ASD | no |
| Allosteric Prediction | no (-1.09149466) |
| Ortholog in Animals | Alpaca_ B4GALNT4 ( ortholog_one2one ) Dog_ B4GALNT4 ( ortholog_one2one ) GuineaPig_ B4GALNT4 ( ortholog_one2one ) Macaque_ B4GALNT4 ( ortholog_one2one ) Mouse_ B4galnt4 ( ortholog_one2one ) Pig_ B4GALNT4 ( ortholog_one2one ) Rat_ B4galnt4 ( ortholog_one2one ) |
| Ohnologs | B4GALNT3 |
| Paralogs | B4GALNT3, CHPF, CHSY3, CHSY1, CHPF2, CSGALNACT2, CSGALNACT1 |
| Tissue | brain, endometrium, ovary, cerebral.cortex |
| Tissue Specificity | Highly expressed in ovary, adult and fetal brain. Also expressed in fetal kidney and lung. {ECO:0000269|PubMed:15044014}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs34063493 rs11822725 |
| Subcellular location [CC] | Golgi apparatus, Golgi stack membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
| Mouse PG classification | NA |
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