| Gene Information | |
|---|---|
| Gene Name | CACNG8 |
| Organism | Homo sapiens (Human) |
| Gene Length | 425 |
| Protein Names | Voltage-dependent calcium channel gamma-8 subunit (Neuronal voltage-gated calcium channel gamma-8 subunit) (Transmembrane AMPAR regulatory protein gamma-8) (TARP gamma-8) |
| Target Name | voltage-dependent calcium channel |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000142408 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8WXS5 |
| Gene Card | CACNG8 |
| Uniprot ID | Q8WXS5 |
| Pfam | PF00822 |
| In ASD | no |
| Allosteric Prediction | yes (0.567752594) |
| Ortholog in Animals | Alpaca_ CACNG8 ( ortholog_one2one ) Dog_ CACNG8 ( ortholog_one2one ) Macaque_ CACNG8 ( ortholog_one2one ) Mouse_ Cacng8 ( ortholog_one2one ) Pig_ CACNG8 ( ortholog_one2one ) Rat_ Cacng8 ( ortholog_one2one ) |
| Ohnologs | CACNG3, CACNG4 |
| Paralogs | CACNG7, CACNG5, CACNG3, CACNG2, CACNG4 |
| Tissue | brain, cerebral.cortex, amygdala, caudate.nucleus, hippocampus, hypothalamus, nucleus.accumbens, putamen |
| Tissue Specificity | Detected in heart left ventricle. {ECO:0000269|PubMed:21127204}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000250|UniProtKB:Q8VHW2}; Multi-pass membrane protein {ECO:0000305}. Postsynaptic density membrane {ECO:0000250|UniProtKB:Q8VHW2}. |
| Mouse PG classification | NA |
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