| Gene Information | |
|---|---|
| Gene Name | B3GNT8 |
| Organism | Homo sapiens (Human) |
| Gene Length | 397 |
| Protein Names | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 (BGnT-8) (Beta-1,3-Gn-T8) (Beta-1,3-N-acetylglucosaminyltransferase 8) (Beta3Gn-T8) (EC 2.4.1.-) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000177191 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q7Z7M8 |
| Gene Card | B3GNT8 |
| Uniprot ID | Q7Z7M8 |
| Pfam | PF01762 |
| In ASD | no |
| Allosteric Prediction | no (-0.985079816) |
| Ortholog in Animals | Alpaca_ B3GNT8 ( ortholog_one2one ) Dog_ B3GNT8 ( ortholog_one2one ) GuineaPig_ B3GNT8 ( ortholog_one2one ) Macaque_ B3GNT8 ( ortholog_one2one ) Mouse_ B3gnt8 ( ortholog_one2one ) Pig_ B3GNT8 ( ortholog_one2one ) Rat_ B3gnt8 ( ortholog_one2one ) Rabbit_ B3GNT8 ( ortholog_one2one ) |
| Ohnologs | B3GNT2, B3GALT1 |
| Paralogs | B3GALT2, B3GALT6, B3GALT1, B3GNT6, B3GALT4, B3GALNT1, B3GALT5, B3GNT4, B3GNT9, B3GNT7, B3GNT2, B3GNT3, B3GNT5, B3GALNT2, B3GALT9 |
| Tissue | colon, duodenum, esophagus, lung, small.intestine |
| Tissue Specificity | Highly expressed in small intestine, pancreas, spleen, bone marrow, lung, throat, and ileum, and weakly in fetal brain, cerebellum, heart, liver, tongue, breast, uteri, and testis. Not detected in colon. Differentially expressed in human tumor cell lines. {ECO:0000269|PubMed:15486459, ECO:0000269|PubMed:15620693}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs284662 |
| Subcellular location [CC] | Golgi apparatus membrane {ECO:0000250|UniProtKB:Q9NY97}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:Q9NY97}. |
| Mouse PG classification | NA |
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