| Gene Information | |
|---|---|
| Gene Name | B3GNT5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 378 |
| Protein Names | Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase (EC 2.4.1.206) (Lactotriaosylceramide synthase) (Lc(3)Cer synthase) (Lc3 synthase) (UDP-GlcNAc:beta-Gal beta-1,3-N-acetylglucosaminyltransferase 5) (BGnT-5) (Beta-1,3-Gn-T5) (Beta-1,3-N-acetylglucosaminyltransferase 5) (Beta3Gn-T5) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 810 ( ENSG00000176597 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9BYG0 |
| Gene Card | B3GNT5 |
| Uniprot ID | Q9BYG0 |
| Pfam | PF01762 |
| In ASD | no |
| Allosteric Prediction | no (-1.293142934) |
| Ortholog in Animals | Alpaca_ B3GNT5 ( ortholog_one2one ) GuineaPig_ B3GNT5 ( ortholog_one2one ) Macaque_ B3GNT5 ( ortholog_one2one ) Mouse_ B3gnt5 ( ortholog_one2one ) Pig_ B3GNT5 ( ortholog_one2one ) Rat_ B3gnt5 ( ortholog_one2one ) Rabbit_ B3GNT5 ( ortholog_one2one ) |
| Ohnologs | B3GNT7 |
| Paralogs | B3GALT2, B3GALT6, B3GNT8, B3GALT1, B3GNT6, B3GALT4, B3GALNT1, B3GALT5, B3GNT4, B3GNT9, B3GNT7, B3GNT2, B3GNT3, B3GALNT2, B3GALT9 |
| Tissue | small.intestine |
| Tissue Specificity | Widely expressed. Highly expressed in lung, colon, placenta, testis, pituitary gland and cerebellum. Weakly expressed in brain, liver, spleen, lymph node and thymus. {ECO:0000269|PubMed:11283017}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
| Mouse PG classification | NA |
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