| Gene Information | |
|---|---|
| Gene Name | ATL2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 583 |
| Protein Names | Atlastin-2 (EC 3.6.5.-) (ADP-ribosylation factor-like protein 6-interacting protein 2) (ARL-6-interacting protein 2) (Aip-2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000119787 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8NHH9 |
| Gene Card | ATL2 |
| Uniprot ID | Q8NHH9 |
| Pfam | PF02263; PF02841 |
| In ASD | no |
| Allosteric Prediction | no (-0.868232225) |
| Ortholog in Animals | Alpaca_ ATL2 ( ortholog_one2one ) Dog_ ATL2 ( ortholog_one2one ) Macaque_ ATL2 ( ortholog_one2one ) Mouse_ Atl2 ( ortholog_one2one ) Pig_ ATL2 ( ortholog_one2one ) Rat_ Atl2 ( ortholog_one2one ) Rabbit_ ATL2 ( ortholog_one2one ) |
| Ohnologs | ATL3, ATL1 |
| Paralogs | ATL1, GBP5, GBP7, ATL3, GBP2, GBP6, GBP1, RNF112, GBP4, GBP3 |
| Tissue | NA |
| Tissue Specificity | Expressed in peripheral tissues (at protein level). {ECO:0000269|PubMed:18270207}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3731847 rs34873284 rs7582826 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:18270207, ECO:0000269|PubMed:27619977}; Multi-pass membrane protein {ECO:0000269|PubMed:18270207}. Note=Localizes at endoplasmic reticulum (ER) three-way tubular junctions (PubMed:27619977). {ECO:0000269|PubMed:27619977}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |