| Gene Information | |
|---|---|
| Gene Name | B3GAT1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 334 |
| Protein Names | Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 (EC 2.4.1.135) (Beta-1,3-glucuronyltransferase 1) (Glucuronosyltransferase P) (GlcAT-P) (UDP-GlcUA:glycoprotein beta-1,3-glucuronyltransferase) (GlcUAT-P) |
| Target Name | galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000109956 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9P2W7 |
| Gene Card | B3GAT1 |
| Uniprot ID | Q9P2W7 |
| Pfam | PF03360 |
| In ASD | no |
| Allosteric Prediction | no (-0.425613813) |
| Ortholog in Animals | Alpaca_ B3GAT1 ( ortholog_one2one ) Dog_ B3GAT1 ( ortholog_one2one ) GuineaPig_ B3GAT1 ( ortholog_one2one ) Macaque_ B3GAT1 ( ortholog_one2one ) Mouse_ B3gat1 ( ortholog_one2one ) Pig_ B3GAT1 ( ortholog_one2one ) Rat_ B3gat1 ( ortholog_one2one ) Rabbit_ B3GAT1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | B3GAT2, B3GAT3 |
| Tissue | brain, cerebral.cortex |
| Tissue Specificity | Mainly expressed in the brain. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1V82 (X-ray 1.85A ) 1V83 (X-ray 1.90A ) 1V84 (X-ray 1.82A ) |
| DBSNP | rs35434644 |
| Subcellular location [CC] | [Isoform 1]: Golgi apparatus membrane {ECO:0000250|UniProtKB:O35789}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:O35789}. Secreted {ECO:0000250|UniProtKB:O35789}.; [Isoform 2]: Golgi apparatus membrane {ECO:0000250|UniProtKB:O35789}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:O35789}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:O35789}. Secreted {ECO:0000250|UniProtKB:O35789}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |