Gene Information
Gene NameSLC24A5
OrganismHomo sapiens (Human)
Gene Length500
Protein NamesSodium/potassium/calcium exchanger 5 (Na(+)/K(+)/Ca(2+)-exchange protein 5) (Solute carrier family 24 member 5)
Target NameNA
Target TypeNA
Gene Age680 ( ENSG00000188467 )
Evolutionary StageCellular_organisms
AlphaFoldDBQ71RS6
Gene CardSLC24A5
Uniprot IDQ71RS6
PfamPF01699
In ASDno
Allosteric Predictionno (-0.811032932)
Ortholog in AnimalsAlpaca_ SLC24A5 ( ortholog_one2one )
Dog_ SLC24A5 ( ortholog_one2one )
GuineaPig_ SLC24A5 ( ortholog_one2one )
Macaque_ SLC24A5 ( ortholog_one2one )
Mouse_ Slc24a5 ( ortholog_one2one )
Pig_ SLC24A5 ( ortholog_one2one )
Rat_ Slc24a5 ( ortholog_one2one )
Rabbit_ SLC24A5 ( ortholog_one2one )
OhnologsNA
ParalogsSLC24A1, SLC24A2, SLC24A3, SLC24A4
Tissuepineal.gland
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs1426654 
Subcellular location [CC]Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:18166528};
Multi-pass membrane protein {ECO:0000255}. Melanosome {ECO:0000269|PubMed:17081065}. Note=Enriched in late-stage melanosomes. {ECO:0000269|PubMed:17081065}.
Mouse PG classificationNA
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