| Gene Information | |
|---|---|
| Gene Name | AXIN2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 843 |
| Protein Names | Axin-2 (Axin-like protein) (Axil) (Axis inhibition protein 2) (Conductin) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000168646 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9Y2T1 |
| Gene Card | AXIN2 |
| Uniprot ID | Q9Y2T1 |
| Pfam | PF16646; PF08833; PF00778; PF00615 |
| In ASD | no |
| Allosteric Prediction | no (-0.446817052) |
| Ortholog in Animals | Alpaca_ AXIN2 ( ortholog_one2one ) Dog_ AXIN2 ( ortholog_one2one ) GuineaPig_ AXIN2 ( ortholog_one2one ) Macaque_ AXIN2 ( ortholog_one2one ) Mouse_ Axin2 ( ortholog_one2one ) Pig_ AXIN2 ( ortholog_one2one ) Rat_ Axin2 ( ortholog_one2one ) Rabbit_ AXIN2 ( ortholog_one2one ) |
| Ohnologs | AXIN1 |
| Paralogs | RGS18, RGS5, RGS3, RGS20, RGS2, RGSL1, RGS12, RGS21, AXIN1, RGS1, RGS11, RGS17, RGS7, RGS14, RGS22, RGS4, RGS6, RGS9, RGS13, RGS19, RGS8, RGS16, RGS10 |
| Tissue | NA |
| Tissue Specificity | Expressed in brain and lymphoblast. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2240308 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:21383061}. |
| Mouse PG classification | LPG |
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