| Gene Information | |
|---|---|
| Gene Name | GABRE |
| Organism | Homo sapiens (Human) |
| Gene Length | 506 |
| Protein Names | Gamma-aminobutyric acid receptor subunit epsilon (GABA(A) receptor subunit epsilon) |
| Target Name | gaba(a) receptor |
| Target Type | NA |
| Gene Age | 424 ( ENSG00000102287 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | P78334 |
| Gene Card | GABRE |
| Uniprot ID | P78334 |
| Pfam | PF02931; PF02932 |
| In ASD | yes |
| Allosteric Prediction | yes (0.999961431) |
| Ortholog in Animals | Alpaca_ GABRE ( ortholog_one2one ) Alpaca_ GABRE ( ortholog_one2many ) Dog_ GABRE ( ortholog_one2one ) GuineaPig_ GABRE ( ortholog_one2one ) Macaque_ GABRE ( ortholog_one2one ) Mouse_ Gabre ( ortholog_one2one ) Pig_ GABRE ( ortholog_one2one ) Rabbit_ GABRE ( ortholog_one2one ) |
| Ohnologs | GABRA1, GABRA4, GABRG2, GABRA2, GABRG1, GABRG3 |
| Paralogs | CHRNB1, GABRR2, CHRNA6, CHRNB4, CHRNA4, GABRQ, HTR3E, CHRNA1, CHRNA3, GABRA5, GLRA2, HTR3B, GLRA1, GABRG3, GABRA2, GABRB3, GABRP, HTR3C, HTR3D, GABRG1, CHRNA7, CHRFAM7A, GABRD, GABRR1, CHRNA5, GABRA6, GABRA4, GLRA3, CHRNE, GABRG2, CHRND, CHRNA2, CHRNA10, CHRNA9, GABRA3, HTR3A, ZACN, CHRNB3, CHRNB2, CHRNG, GABRR3, GABRB2, GABRB1, GABRA1, GLRB |
| Tissue | NA |
| Tissue Specificity | Expressed in many tissues. Highest levels of expression in adult heart and placenta. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs17855708 rs1139916 |
| Subcellular location [CC] | Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
| click here to return to the previous page | |