| Gene Information | |
|---|---|
| Gene Name | AUNIP |
| Organism | Homo sapiens (Human) |
| Gene Length | 357 |
| Protein Names | Aurora kinase A and ninein-interacting protein (AIBp) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 332 ( ENSG00000127423 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q9H7T9 |
| Gene Card | AUNIP |
| Uniprot ID | Q9H7T9 |
| Pfam | PF15334 |
| In ASD | no |
| Allosteric Prediction | no (-1.45716809) |
| Ortholog in Animals | Alpaca_ AUNIP ( ortholog_one2one ) Dog_ AUNIP ( ortholog_one2one ) GuineaPig_ AUNIP ( ortholog_one2one ) Macaque_ AUNIP ( ortholog_one2one ) Mouse_ Aunip ( ortholog_one2one ) Pig_ AUNIP ( ortholog_one2one ) Rat_ Aunip ( ortholog_one2one ) Rabbit_ AUNIP ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | testis |
| Tissue Specificity | Expressed in heart, skeletal muscles, placenta and testis. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs34449716 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:29042561}. Chromosome {ECO:0000269|PubMed:29042561}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:20596670}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000269|PubMed:20596670}. Note=Accumulates at sites of DNA damage by binding to DNA substrates that mimick structures generated at stalled replication forks (PubMed:29042561). Localizes to the centrosome in interphase and to the spindle pole in metaphase (PubMed:20596670). {ECO:0000269|PubMed:20596670, ECO:0000269|PubMed:29042561}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |