| Gene Information | |
|---|---|
| Gene Name | EVI5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 810 |
| Protein Names | Ecotropic viral integration site 5 protein homolog (EVI-5) (Neuroblastoma stage 4S gene protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000067208 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O60447 |
| Gene Card | EVI5 |
| Uniprot ID | O60447 |
| Pfam | PF00566 |
| In ASD | no |
| Allosteric Prediction | no (-1.144156478) |
| Ortholog in Animals | Alpaca_ EVI5 ( ortholog_one2one ) Dog_ EVI5 ( ortholog_one2one ) GuineaPig_ EVI5 ( ortholog_one2one ) Macaque_ EVI5 ( ortholog_one2one ) Mouse_ Evi5 ( ortholog_one2one ) Pig_ EVI5 ( ortholog_one2one ) Rat_ Evi5 ( ortholog_one2one ) Rabbit_ EVI5 ( ortholog_one2one ) |
| Ohnologs | EVI5L |
| Paralogs | TBC1D3C, TBC1D3D, TBC1D3, TBC1D3G, TBC1D3B, TBC1D3F, TBC1D3I, TBC1D3E, TBC1D3L, TBC1D3H, TBC1D3K, TBC1D8, TBC1D14, TBC1D10A, SGSM1, TBC1D8B, TBC1D2B, TBC1D10B, RABGAP1, TBC1D17, TBC1D9B, TBC1D25, TBC1D30, TBC1D26, TBC1D28, TBC1D22A, USP6NL, TBC1D9, RABGAP1L, TBC1D2, TBC1D13, TBC1D12, SGSM2, TBC1D4, GRTP1, TBC1D15, SGSM3, TBC1D16, TBCK, TBC1D22B, TBC1D5, TBC1D1, TBC1D10C, TBC1D21, EVI5L |
| Tissue | NA |
| Tissue Specificity | Expressed in various cell lines (at protein level). Expressed in a wide range of tissues including brain and adrenal. {ECO:0000269|PubMed:16033705, ECO:0000269|PubMed:9618176}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1064580 rs2391199 rs11808092 |
| Subcellular location [CC] | Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Associates with the mitotic spindle through anaphase and remains within the midzone and midbody until completion of cytokinesis. |
| Mouse PG classification | NA |
| click here to return to the previous page | |