| Gene Information | |
|---|---|
| Gene Name | ANKLE2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 938 |
| Protein Names | Ankyrin repeat and LEM domain-containing protein 2 (LEM domain-containing protein 4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000176915 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q86XL3 |
| Gene Card | ANKLE2 |
| Uniprot ID | Q86XL3 |
| Pfam | PF01693; PF03020 |
| In ASD | no |
| Allosteric Prediction | no (-0.949856125) |
| Ortholog in Animals | Alpaca_ ANKLE2 ( ortholog_one2one ) Dog_ ANKLE2 ( ortholog_one2one ) GuineaPig_ ANKLE2 ( ortholog_one2one ) Macaque_ ANKLE2 ( ortholog_one2one ) Mouse_ Ankle2 ( ortholog_one2one ) Pig_ ANKLE2 ( ortholog_one2one ) Rat_ Ankle2 ( ortholog_one2one ) Rabbit_ ANKLE2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs986142623 rs1132375 rs7968520 rs1185537869 rs753596204 rs761627940 rs863225465 rs10781634 rs201785518 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:22770216}; Single-pass type III membrane protein {ECO:0000269|PubMed:22770216}. |
| Mouse PG classification | NA |
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