| Gene Information | |
|---|---|
| Gene Name | NKRF |
| Organism | Homo sapiens (Human) |
| Gene Length | 690 |
| Protein Names | NF-kappa-B-repressing factor (NFkB-repressing factor) (NRF) (Protein ITBA4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000186416 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O15226 |
| Gene Card | NKRF |
| Uniprot ID | O15226 |
| Pfam | PF01585; PF01424 |
| In ASD | no |
| Allosteric Prediction | no (-0.678997846) |
| Ortholog in Animals | Alpaca_ NKRF ( ortholog_one2one ) Dog_ NKRF ( ortholog_one2one ) GuineaPig_ NKRF ( ortholog_one2one ) Macaque_ STEEP1 ( ortholog_one2one ) Mouse_ Nkrf ( ortholog_one2one ) Pig_ NKRF ( ortholog_one2one ) Rat_ Nkrf ( ortholog_one2one ) Rabbit_ NKRF ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CDKN2AIPNL, CDKN2AIP |
| Tissue | NA |
| Tissue Specificity | Widely and constitutively expressed (PubMed:10562553). Expressed at lower level in colon, peripheral blood lymphocytes, lung and kidney (PubMed:10562553). {ECO:0000269|PubMed:10562553}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6SH6 (X-ray 1.85A ) 6SH7 (X-ray 2.21A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus, nucleolus {ECO:0000269|PubMed:12429849}. |
| Mouse PG classification | NA |
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