| Gene Information | |
|---|---|
| Gene Name | ATP6V1G1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 118 |
| Protein Names | V-type proton ATPase subunit G 1 (V-ATPase subunit G 1) (V-ATPase 13 kDa subunit 1) (Vacuolar proton pump subunit G 1) (Vacuolar proton pump subunit M16) |
| Target Name | v-atpase subunits |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000136888 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O75348 |
| Gene Card | ATP6V1G1 |
| Uniprot ID | O75348 |
| Pfam | PF03179 |
| In ASD | no |
| Allosteric Prediction | no (-0.828052495) |
| Ortholog in Animals | Alpaca_ ATP6V1G1 ( ortholog_one2one ) Dog_ ATP6V1G1 ( ortholog_one2one ) GuineaPig_ ATP6V1G1 ( ortholog_one2one ) Macaque_ ATP6V1G1 ( ortholog_one2one ) Mouse_ Atp6v1g1 ( ortholog_one2one ) Pig_ ATP6V1G1 ( ortholog_one2one ) Rat_ AABR07029470.2 ( ortholog_one2one ) Rabbit_ ATP6V1G1 ( ortholog_one2one ) |
| Ohnologs | ATP6V1G3, ATP6V1G2 |
| Paralogs | ATP6V1G2, ATP6V1G3 |
| Tissue | NA |
| Tissue Specificity | Kidney; localizes to early distal nephron, encompassing thick ascending limbs and distal convoluted tubules (at protein level) (PubMed:29993276). Ubiquitous (PubMed:12384298). {ECO:0000269|PubMed:12384298, ECO:0000269|PubMed:29993276}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6WLZ (EM 2.90A ) 6WM2 (EM 3.10A ) 6WM3 (EM 3.40A ) 6WM4 (EM 3.60A ) 7U4T (EM 3.60A ) 7UNF (EM 4.08A ) |
| DBSNP | NA |
| Subcellular location [CC] | Apical cell membrane {ECO:0000269|PubMed:29993276}. |
| Mouse PG classification | NA |
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