| Gene Information | |
|---|---|
| Gene Name | ATP6V0A2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 856 |
| Protein Names | V-type proton ATPase 116 kDa subunit a 2 (V-ATPase 116 kDa subunit a 2) (Lysosomal H(+)-transporting ATPase V0 subunit a 2) (TJ6) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 2) |
| Target Name | v-atpase subunits |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000185344 ) |
| Evolutionary Stage | Euk_Archaea |
| AlphaFoldDB | Q9Y487 |
| Gene Card | ATP6V0A2 |
| Uniprot ID | Q9Y487 |
| Pfam | PF01496 |
| In ASD | no |
| Allosteric Prediction | yes (0.242048956) |
| Ortholog in Animals | Alpaca_ ATP6V0A2 ( ortholog_one2one ) Dog_ ATP6V0A2 ( ortholog_one2one ) GuineaPig_ ATP6V0A2 ( ortholog_one2one ) Macaque_ ATP6V0A2 ( ortholog_one2one ) Mouse_ Atp6v0a2 ( ortholog_one2one ) Pig_ ATP6V0A2 ( ortholog_one2one ) |
| Ohnologs | ATP6V0A4, TCIRG1 |
| Paralogs | TCIRG1, ATP6V0A4, ATP6V0A1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs7969410 rs17883456 |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. Endosome membrane. Note=In kidney proximal tubules, also detected in subapical vesicles. {ECO:0000250}. |
| Mouse PG classification | NA |
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