Gene Information
Gene NameHTR1F
OrganismHomo sapiens (Human)
Gene Length366
Protein Names5-hydroxytryptamine receptor 1F (5-HT-1F) (5-HT1F) (Serotonin receptor 1F)
Target Name5-hydroxytryptamine receptor 1
Target TypeNA
Gene Age886 ( ENSG00000179097 )
Evolutionary StageEumetazoa
AlphaFoldDBP30939
Gene CardHTR1F
Uniprot IDP30939
PfamPF00001
In ASDno
Allosteric Predictionyes (0.912772311)
Ortholog in AnimalsAlpaca_ HTR1F ( ortholog_one2one )
Dog_ HTR1F ( ortholog_one2one )
Mouse_ Htr1f ( ortholog_one2one )
Pig_ HTR1F ( ortholog_one2one )
Rat_ Htr1f ( ortholog_one2one )
Rabbit_ HTR1F ( ortholog_one2one )
OhnologsHTR1B, HTR1E, HTR1A, HTR1D
ParalogsHTR1E, HTR1B, HTR5A, HTR7, HTR6, HTR2C, HTR2A, HTR2B
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 7EXD  (EM  3.40A 
DBSNP NA 
Subcellular location [CC]Cell membrane {ECO:0000269|PubMed:8380639, ECO:0000269|PubMed:8384716};
Multi-pass membrane protein {ECO:0000269|PubMed:8380639, ECO:0000269|PubMed:8384716}.
Mouse PG classificationNA
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