Gene Information
Gene NameGALE
OrganismHomo sapiens (Human)
Gene Length348
Protein NamesUDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase) (UDP-N-acetylgalactosamine 4-epimerase) (UDP-GalNAc 4-epimerase) (UDP-N-acetylglucosamine 4-epimerase) (UDP-GlcNAc 4-epimerase) (EC 5.1.3.7) (UDP-galactose 4-epimerase)
Target Nameudp-glucose 4-epimerase
Target TypeLiterature-reported target
Gene Age1488 ( ENSG00000117308 )
Evolutionary StageEuk+Bac
AlphaFoldDBQ14376
Gene CardGALE
Uniprot IDQ14376
PfamPF16363
In ASDno
Allosteric Predictionyes (0.437962717)
Ortholog in AnimalsAlpaca_ GALE ( ortholog_one2one )
Dog_ GALE ( ortholog_one2one )
GuineaPig_ GALE ( ortholog_one2one )
Macaque_ GALE ( ortholog_one2one )
Mouse_ Gale ( ortholog_one2one )
Pig_ GALE ( ortholog_one2one )
Rat_ Gale ( ortholog_one2one )
Rabbit_ GALE ( ortholog_one2one )
OhnologsNA
ParalogsHSD3B7, GFUS, HSD3B2, HSD3B1, SDR42E2, SDR42E1, GMDS, TGDS, UXS1, NSDHL
Tissuegall.bladder, submandibular.gland
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1EK5  (X-ray  1.80A  )  1EK6  (X-ray  1.50A  )  1HZJ  (X-ray  1.50A  )  1I3K  (X-ray  1.50A  )  1I3L  (X-ray  1.50A  )  1I3M  (X-ray  1.50A  )  1I3N  (X-ray  1.50A  ) 
DBSNP rs1431772923  rs121908046  rs144492228  rs1261697960  rs28940882  rs121908047  rs28940883  rs528467258  rs137853859  rs3204468  rs121908045  rs137853860  rs28940884  rs137853861  rs3180383  rs28940885  rs368637540 
Subcellular location [CC]NA
Mouse PG classificationNA
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