| Gene Information | |
|---|---|
| Gene Name | PNLIP |
| Organism | Homo sapiens (Human) |
| Gene Length | 465 |
| Protein Names | Pancreatic triacylglycerol lipase (PL) (PTL) (Pancreatic lipase) (EC 3.1.1.3) |
| Target Name | pancreatic triacylglycerol lipase |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000175535 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P16233 |
| Gene Card | PNLIP |
| Uniprot ID | P16233 |
| Pfam | PF00151; PF01477 |
| In ASD | yes |
| Allosteric Prediction | yes (0.318204023) |
| Ortholog in Animals | Alpaca_ PNLIP ( ortholog_one2one ) GuineaPig_ PNLIP ( ortholog_one2one ) Macaque_ PNLIP ( ortholog_one2one ) Mouse_ Pnlip ( ortholog_one2one ) Pig_ PNLIP ( ortholog_one2one ) Rat_ Pnlip ( ortholog_one2one ) Rabbit_ PNLIP ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | PLA1A, PNLIPRP3, LIPI, LIPC, PNLIPRP2, LIPH, PNLIPRP1, LIPG, LPL |
| Tissue | pancreas |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1GPL (X-ray 2.01A ) 1LPA (X-ray 3.04A ) 1LPB (X-ray 2.46A ) 1N8S (X-ray 3.04A ) |
| DBSNP | rs746000327 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:25862608}. |
| Mouse PG classification | NA |
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