| Gene Information | |
|---|---|
| Gene Name | ATP4B |
| Organism | Homo sapiens (Human) |
| Gene Length | 291 |
| Protein Names | Potassium-transporting ATPase subunit beta (Gastric H(+)/K(+) ATPase subunit beta) (Proton pump beta chain) |
| Target Name | potassium-transporting atpase subunit beta |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000186009 ) 3 ( ENSG00000288359 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P51164 |
| Gene Card | ATP4B |
| Uniprot ID | P51164 |
| Pfam | PF00287 |
| In ASD | no |
| Allosteric Prediction | no (-0.375082223) |
| Ortholog in Animals | Alpaca_ ATP4B ( ortholog_one2one ) Dog_ ATP4B ( ortholog_one2one ) GuineaPig_ ATP4B ( ortholog_one2one ) Macaque_ ATP4B ( ortholog_one2one ) Mouse_ Atp4b ( ortholog_one2one ) Pig_ ATP4B ( ortholog_one2one ) Rat_ Atp4b ( ortholog_one2one ) Rabbit_ ATP4B ( ortholog_one2one ) |
| Ohnologs | ATP1B4, ATP1B2, ATP1B3 |
| Paralogs | ATP1B4, ATP1B1, ATP1B2, ATP1B3 |
| Tissue | stomach |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);NULL(Rat);0.200000(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Apical cell membrane {ECO:0000250|UniProtKB:P20648}; Single-pass type II membrane protein {ECO:0000255}. Cell membrane {ECO:0000250|UniProtKB:P18597}; Single-pass type II membrane protein {ECO:0000255}. Note=Localized in the apical canalicular membrane of parietal cells. {ECO:0000250|UniProtKB:P20648}. |
| Mouse PG classification | NA |
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