| Gene Information | |
|---|---|
| Gene Name | GJB7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 223 |
| Protein Names | Gap junction beta-7 protein (Connexin-25) (Cx25) |
| Target Name | connexin-25 |
| Target Type | Literature-reported target |
| Gene Age | 36 ( ENSG00000164411 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q6PEY0 |
| Gene Card | GJB7 |
| Uniprot ID | Q6PEY0 |
| Pfam | PF00029 |
| In ASD | no |
| Allosteric Prediction | no (-0.50262463) |
| Ortholog in Animals | Alpaca_ GJB7 ( ortholog_one2one ) Dog_ GJB7 ( ortholog_one2one ) Pig_ GJB7 ( ortholog_one2one ) Rabbit_ GJB7 ( ortholog_one2one ) |
| Ohnologs | GJB6, GJB2, GJB1, GJB3, GJB5, GJB4 |
| Paralogs | GJB3, GJB5, GJB4, GJB1, GJB2, GJB6, GJA4, GJA1, GJA8, GJA5, GJA3, GJA10, GJA9, GJD2, GJD3, GJC3, GJC2, GJC1, GJD4, GJE1 |
| Tissue | NA |
| Tissue Specificity | Weakly expressed in placenta. {ECO:0000269|PubMed:12881038}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs4707358 rs41273281 rs6934603 |
| Subcellular location [CC] | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell junction, gap junction {ECO:0000250}. |
| Mouse PG classification | NA |
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