| Gene Information | |
|---|---|
| Gene Name | ATP1A4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1029 |
| Protein Names | Sodium/potassium-transporting ATPase subunit alpha-4 (Na(+)/K(+) ATPase alpha-4 subunit) (EC 7.2.2.13) (Sodium pump subunit alpha-4) |
| Target Name | sodium/potassium transporting atpase subunits |
| Target Type | NA |
| Gene Age | 244 ( ENSG00000132681 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q13733 |
| Gene Card | ATP1A4 |
| Uniprot ID | Q13733 |
| Pfam | PF00689; PF00690 |
| In ASD | no |
| Allosteric Prediction | yes (0.196166457) |
| Ortholog in Animals | Alpaca_ ATP1A4 ( ortholog_one2one ) GuineaPig_ ATP1A4 ( ortholog_one2one ) Macaque_ ATP1A4 ( ortholog_one2one ) Mouse_ Atp1a4 ( ortholog_one2one ) Pig_ ATP1A4 ( ortholog_one2one ) Rat_ Atp1a4 ( ortholog_one2one ) Rabbit_ ATP1A4 ( ortholog_one2one ) |
| Ohnologs | ATP1A3, ATP1A1 |
| Paralogs | ATP2B4, ATP13A3, ATP7A, ATP2A3, ATP2B3, ATP1A3, ATP13A2, ATP2B2, ATP13A4, ATP7B, ATP13A5, ATP12A, ATP2B1, ATP2C2, ATP1A1, ATP1A2, ATP2A1, ATP2A2, ATP4A, ATP2C1, ATP13A1 |
| Tissue | testis, urinary.bladder |
| Tissue Specificity | Specifically expressed in testis. Found in very low levels in skeletal muscle. Expressed in mature sperm (at protein level). |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.05(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs6427504 rs17368402 rs16831482 rs7528360 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:16175638}; Multi-pass membrane protein {ECO:0000269|PubMed:16175638}. Note=In mature sperm, located in the principle piece of the sperm flagellum. |
| Mouse PG classification | NA |
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