| Gene Information | |
|---|---|
| Gene Name | ATP1A3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1013 |
| Protein Names | Sodium/potassium-transporting ATPase subunit alpha-3 (Na(+)/K(+) ATPase alpha-3 subunit) (EC 7.2.2.13) (Na(+)/K(+) ATPase alpha(III) subunit) (Sodium pump subunit alpha-3) |
| Target Name | sodium/potassium-transporting atpase subunit alpha-3 |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000105409 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P13637 |
| Gene Card | ATP1A3 |
| Uniprot ID | P13637 |
| Pfam | PF00689; PF00690 |
| In ASD | no |
| Allosteric Prediction | yes (1.124793543) |
| Ortholog in Animals | Alpaca_ ATP1A3 ( ortholog_one2one ) Dog_ ATP1A3 ( ortholog_one2one ) GuineaPig_ ATP1A3 ( ortholog_one2one ) Macaque_ ATP1A3 ( ortholog_one2one ) Mouse_ Atp1a3 ( ortholog_one2one ) Pig_ ATP1A3 ( ortholog_one2one ) Rat_ Atp1a3 ( ortholog_one2one ) Rabbit_ ATP1A3 ( ortholog_one2one ) |
| Ohnologs | ATP1A2, ATP1A4 |
| Paralogs | ATP2B4, ATP13A3, ATP7A, ATP2A3, ATP2B3, ATP13A2, ATP2B2, ATP13A4, ATP7B, ATP13A5, ATP12A, ATP2B1, ATP1A4, ATP2C2, ATP1A1, ATP1A2, ATP2A1, ATP2A2, ATP4A, ATP2C1, ATP13A1 |
| Tissue | brain, heart, cerebral.cortex |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.003490(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs542652468 rs542652468 rs606231427 rs1396898460 rs80356532 rs80356532 rs80356533 rs879255368 rs606231428 rs606231430 rs606231433 rs80356534 rs557052809 rs557052809 rs80356535 rs534926223 rs606231437 rs606231437 rs80356536 rs80356537 rs80356537 rs549006436 rs536681257 rs387907282 rs387907281 rs587777771 rs606231443 rs267606670 rs267606670 rs1555859157 rs606231444 rs398122887 rs606231446 rs606231447 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:7711835}; Multi-pass membrane protein {ECO:0000269|PubMed:7711835}. |
| Mouse PG classification | NA |
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