| Gene Information | |
|---|---|
| Gene Name | CCDC88B |
| Organism | Homo sapiens (Human) |
| Gene Length | 1476 |
| Protein Names | Coiled-coil domain-containing protein 88B (Brain leucine zipper domain-containing protein) (Gipie) (Hook-related protein 3) (HkRP3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 244 ( ENSG00000168071 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | A6NC98 |
| Gene Card | CCDC88B |
| Uniprot ID | A6NC98 |
| Pfam | PF19047 |
| In ASD | no |
| Allosteric Prediction | no (-1.427325102) |
| Ortholog in Animals | Alpaca_ CCDC88B ( ortholog_one2many ) Dog_ CCDC88B ( ortholog_one2one ) GuineaPig_ CCDC88B ( ortholog_one2one ) Macaque_ CCDC88B ( ortholog_one2one ) Mouse_ Ccdc88b ( ortholog_one2one ) Rat_ Ccdc88b ( ortholog_one2one ) |
| Ohnologs | CCDC88C, CCDC88A |
| Paralogs | HOOK3, HOOK1, CCDC88A, CCDC88C, HOOK2 |
| Tissue | spleen |
| Tissue Specificity | Expressed in endothelium (at protein level) (PubMed:21289099). Expressed in NK cells (at protein level) (PubMed:25762780). {ECO:0000269|PubMed:21289099, ECO:0000269|PubMed:25762780}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs647152 rs685870 rs1318165 |
| Subcellular location [CC] | Membrane {ECO:0000250|UniProtKB:Q4QRL3}; Peripheral membrane protein {ECO:0000305}. Cytoplasm, cytoskeleton, microtubule organizing center {ECO:0000269|PubMed:25762780}. Endoplasmic reticulum {ECO:0000269|PubMed:21289099}. Golgi apparatus {ECO:0000269|PubMed:21289099}. Cytoplasm {ECO:0000269|PubMed:21289099}. |
| Mouse PG classification | NA |
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