| Gene Information | |
|---|---|
| Gene Name | ATOH8 |
| Organism | Homo sapiens (Human) |
| Gene Length | 321 |
| Protein Names | Transcription factor ATOH8 (Class A basic helix-loop-helix protein 21) (bHLHa21) (Helix-loop-helix protein hATH-6) (hATH6) (Protein atonal homolog 8) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000168874 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q96SQ7 |
| Gene Card | ATOH8 |
| Uniprot ID | Q96SQ7 |
| Pfam | PF00010 |
| In ASD | no |
| Allosteric Prediction | no (-1.283919842) |
| Ortholog in Animals | Alpaca_ ATOH8 ( ortholog_one2one ) Dog_ ATOH8 ( ortholog_one2one ) GuineaPig_ ATOH8 ( ortholog_one2one ) Macaque_ ATOH8 ( ortholog_one2one ) Mouse_ Atoh8 ( ortholog_one2one ) Pig_ ATOH8 ( ortholog_one2one ) Rat_ Atoh8 ( ortholog_one2one ) Rabbit_ ATOH8 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | BHLHE23, BHLHA15, NEUROD6, OLIG2, NEUROG1, ATOH1, ATOH7, NEUROG2, BHLHE22, NEUROD4, OLIG3, NEUROD1, NEUROG3, OLIG1, NEUROD2 |
| Tissue | NA |
| Tissue Specificity | Expressed in lung, liver, kidney, heart and pancreas. Expressed in endothel of umbilical vessels. {ECO:0000269|PubMed:12419857}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs17851881 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:24463812}. Nucleus speckle {ECO:0000269|PubMed:24463812}. Cytoplasm {ECO:0000250|UniProtKB:Q99NA2}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |