| Gene Information | |
|---|---|
| Gene Name | ATG13 |
| Organism | Homo sapiens (Human) |
| Gene Length | 517 |
| Protein Names | Autophagy-related protein 13 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000175224 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O75143 |
| Gene Card | ATG13 |
| Uniprot ID | O75143 |
| Pfam | PF10033 |
| In ASD | no |
| Allosteric Prediction | no (-0.635970937) |
| Ortholog in Animals | Alpaca_ ATG13 ( ortholog_one2one ) Dog_ ATG13 ( ortholog_one2one ) GuineaPig_ ATG13 ( ortholog_one2one ) Macaque_ ATG13 ( ortholog_one2one ) Mouse_ Atg13 ( ortholog_one2one ) Pig_ ATG13 ( ortholog_one2one ) Rat_ Atg13 ( ortholog_one2one ) Rabbit_ ATG13 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.047059(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3WAN (X-ray 1.77A ) 3WAO (X-ray 2.60A ) 3WAP (X-ray 3.10A ) 5C50 (X-ray 1.63A ) 5XUY (X-ray 2.20A ) 5XV1 (X-ray 2.51A ) 5XV3 (X-ray 2.57A ) 5XV4 (X-ray 2.95A ) 5XV6 (X-ray 2.46A ) 6HYN (X-ray 1.14A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000269|PubMed:19211835}. Preautophagosomal structure {ECO:0000269|PubMed:19211835}. Note=Under starvation conditions, is localized to puncate structures primarily representing the isolation membrane; the isolation membrane sequesters a portion of the cytoplasm resulting in autophagosome formation. {ECO:0000269|PubMed:19211835}. |
| Mouse PG classification | NA |
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