Gene Information | |
---|---|
Gene Name | ATF5 |
Organism | Homo sapiens (Human) |
Gene Length | 282 |
Protein Names | Cyclic AMP-dependent transcription factor ATF-5 (cAMP-dependent transcription factor ATF-5) (Activating transcription factor 5) (Transcription factor ATFx) |
Target Name | activator protein 1 |
Target Type | NA |
Gene Age | 454 ( ENSG00000169136 ) |
Evolutionary Stage | Eumetazoa |
AlphaFoldDB | Q9Y2D1 |
Gene Card | ATF5 |
Uniprot ID | Q9Y2D1 |
Pfam | PF00170 |
In ASD | no |
Allosteric Prediction | no (-0.640876884) |
Ortholog in Animals | Alpaca_ ATF5 ( ortholog_one2one ) GuineaPig_ ATF5 ( ortholog_one2one ) Macaque_ ATF5 ( ortholog_one2one ) Mouse_ Atf5 ( ortholog_one2one ) Pig_ ATF5 ( ortholog_one2one ) Rat_ Atf5 ( ortholog_one2one ) |
Ohnologs | NA |
Paralogs | ATF4 |
Tissue | NA |
Tissue Specificity | Widely expressed with higher expression levels in liver. {ECO:0000269|PubMed:18332083}. |
Pharmacological Animal Models | NA |
Gene Ontology (biological process) |
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Gene Ontology (cellular component) |
|
Gene Ontology (molecular function) |
|
PDB | NA |
DBSNP | rs283526 |
Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:15358120}. Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978, ECO:0000269|PubMed:15358120, ECO:0000269|PubMed:22528486}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:26213385}. Note=Actively transported to the centrosome and accumulated in the pericentriolar material (PCM) during G1 to M phase via a microtubule-dependent mechanism. During late telophase and cytokinesis, translocates from the centrosome to the midbody. {ECO:0000269|PubMed:26213385}. |
Mouse PG classification | NA |
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