Gene Information
Gene NameATF5
OrganismHomo sapiens (Human)
Gene Length282
Protein NamesCyclic AMP-dependent transcription factor ATF-5 (cAMP-dependent transcription factor ATF-5) (Activating transcription factor 5) (Transcription factor ATFx)
Target Nameactivator protein 1
Target TypeNA
Gene Age454 ( ENSG00000169136 )
Evolutionary StageEumetazoa
AlphaFoldDBQ9Y2D1
Gene CardATF5
Uniprot IDQ9Y2D1
PfamPF00170
In ASDno
Allosteric Predictionno (-0.640876884)
Ortholog in AnimalsAlpaca_ ATF5 ( ortholog_one2one )
GuineaPig_ ATF5 ( ortholog_one2one )
Macaque_ ATF5 ( ortholog_one2one )
Mouse_ Atf5 ( ortholog_one2one )
Pig_ ATF5 ( ortholog_one2one )
Rat_ Atf5 ( ortholog_one2one )
OhnologsNA
ParalogsATF4
TissueNA
Tissue SpecificityWidely expressed with higher expression levels in liver. {ECO:0000269|PubMed:18332083}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs283526 
Subcellular location [CC]Cytoplasm {ECO:0000269|PubMed:15358120}. Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978, ECO:0000269|PubMed:15358120, ECO:0000269|PubMed:22528486}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:26213385}. Note=Actively transported to the centrosome and accumulated in the pericentriolar material (PCM) during G1 to M phase via a microtubule-dependent mechanism. During late telophase and cytokinesis, translocates from the centrosome to the midbody. {ECO:0000269|PubMed:26213385}.
Mouse PG classificationNA
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