| Gene Information | |
|---|---|
| Gene Name | SCAPIN1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 559 |
| Protein Names | Phosphatase and actin regulator 3 (Scaffold-associated PP1-inhibiting protein) (Scapinin) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q96KR7 |
| Gene Card | PHACTR3 |
| Uniprot ID | Q96KR7 |
| Pfam | PF02755 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Abundantly expressed in brain. Also found in several tumors such as lung carcinomas, nervous tumors and HL-60 leukemia cells. Isoform 3 is the major form in U-937, GOTO and HL-60 leukemia cells. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2277759 |
| Subcellular location [CC] | Nucleus matrix. Note=Localized to the nuclear matrix-intermediate filament scaffold. Isoform 2 is also found in some cytoplasmic extensions. |
| Mouse PG classification | NA |
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