Gene Information
Gene NameASTN
OrganismHomo sapiens (Human)
Gene Length1302
Protein NamesAstrotactin-1
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBO14525
Gene CardASTN1
Uniprot IDO14525
PfamPF18411; PF19743; PF19441
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs2228956  rs2281180  rs12118933  rs12118933 
Subcellular location [CC]Cell membrane {ECO:0000250|UniProtKB:Q61137};
Multi-pass membrane protein {ECO:0000250|UniProtKB:Q61137}. Perikaryon {ECO:0000250|UniProtKB:Q61137}. Endosome {ECO:0000250|UniProtKB:Q61137}. Cytoplasmic vesicle, clathrin-coated vesicle {ECO:0000250|UniProtKB:Q61137}. Note=Detected close to the anterior pole and at the base of the leading process in migrating neurons. Is internalized from the membrane via clathrin-coated vesicles and endosomes, and recycled to the anterior pole of the migrating cell. {ECO:0000250|UniProtKB:Q61137}.
Mouse PG classificationNA
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