| Gene Information | |
|---|---|
| Gene Name | ASPRV1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 343 |
| Protein Names | Retroviral-like aspartic protease 1 (EC 3.4.23.-) (Skin-specific retroviral-like aspartic protease) (SASPase) (Skin aspartic protease) (TPA-inducible aspartic proteinase-like protein) (TAPS) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000244617 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q53RT3 |
| Gene Card | ASPRV1 |
| Uniprot ID | Q53RT3 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.023792201) |
| Ortholog in Animals | Alpaca_ ASPRV1 ( ortholog_one2one ) Macaque_ ASPRV1 ( ortholog_one2one ) Mouse_ Asprv1 ( ortholog_one2one ) Pig_ ASPRV1 ( ortholog_one2one ) Rabbit_ ASPRV1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | skin, lower.leg.skin, suprapubic.skin |
| Tissue Specificity | Expressed primarily in the granular layer of the epidermis and inner root sheath of hair follicles. In psoriatic skin, expressed throughout the stratum corneum. In ulcerated skin, expressed in the stratum granulosum of intact epidermis but almost absent from ulcerated regions. Expressed in differentiated areas of squamous cell carcinomas but not in undifferentiated tumors. {ECO:0000269|PubMed:16098038, ECO:0000269|PubMed:16565508}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3796097 |
| Subcellular location [CC] | Membrane {ECO:0000255}; Single-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |