| Gene Information | |
|---|---|
| Gene Name | ASMTL |
| Organism | Homo sapiens (Human) |
| Gene Length | 621 |
| Protein Names | Probable bifunctional dTTP/UTP pyrophosphatase/methyltransferase protein [Includes: dTTP/UTP pyrophosphatase (dTTPase/UTPase) (EC 3.6.1.9) (Nucleoside triphosphate pyrophosphatase) (Nucleotide pyrophosphatase) (Nucleotide PPase); N-acetylserotonin O-methyltransferase-like protein (ASMTL) (EC 2.1.1.-)] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000169093 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | O95671 |
| Gene Card | ASMTL |
| Uniprot ID | O95671 |
| Pfam | PF16864; PF02545; PF00891 |
| In ASD | no |
| Allosteric Prediction | no (-0.538633753) |
| Ortholog in Animals | Alpaca_ ASMTL ( ortholog_one2one ) Dog_ ASMTL ( ortholog_one2one ) Pig_ ASMTL ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ASMT |
| Tissue | NA |
| Tissue Specificity | Widely expressed. In adult, highly expressed in pancreas, placenta, fibroblast, thymus, prostate, testis, ovary and colon. Expressed at lower levels in spleen, small intestine and leukocytes. In fetus, expressed at high levels in the lung and kidney and at lower level in brain and liver. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2P5X (X-ray 2.00A ) 6XI4 (X-ray 2.22A ) 6XI5 (X-ray 2.61A ) |
| DBSNP | rs4503285 rs1127297 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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