| Gene Information | |
|---|---|
| Gene Name | GIMAP8 |
| Organism | Homo sapiens (Human) |
| Gene Length | 665 |
| Protein Names | GTPase IMAP family member 8 (Immune-associated nucleotide-binding protein 9) (IAN-9) (Protein IanT) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 101 ( ENSG00000171115 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8ND71 |
| Gene Card | GIMAP8 |
| Uniprot ID | Q8ND71 |
| Pfam | PF04548 |
| In ASD | no |
| Allosteric Prediction | no (-0.797876062) |
| Ortholog in Animals | Alpaca_ GIMAP8 ( ortholog_one2many ) Dog_ GIMAP8 ( ortholog_one2one ) Macaque_ GIMAP8 ( ortholog_one2one ) Mouse_ Gimap8 ( ortholog_one2one ) Pig_ GIMAP8 ( ortholog_one2one ) Rat_ Gimap8 ( ortholog_one2one ) Rabbit_ GIMAP8 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | GIMAP6, GIMAP5, GIMAP4, GIMD1, GIMAP1, GIMAP2, GIMAP7 |
| Tissue | NA |
| Tissue Specificity | Expressed in the spleen, intestine, liver, and colon, as well as in lung, placenta, kidney, muscle, and heart. Extremely low expression, if any, in brain, in thymus, bone marrow, and blood leukocytes (PubMed:15474311). Detected in T-cells (PubMed:23454188). {ECO:0000269|PubMed:15474311, ECO:0000269|PubMed:23454188}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2293283 |
| Subcellular location [CC] | Endoplasmic reticulum {ECO:0000250|UniProtKB:Q75N62}. Golgi apparatus {ECO:0000250|UniProtKB:Q75N62}. Mitochondrion {ECO:0000250|UniProtKB:Q75N62}. Cytoplasm, cytosol {ECO:0000269|PubMed:23454188}. |
| Mouse PG classification | NA |
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