Gene Information
Gene NameASIC5
OrganismHomo sapiens (Human)
Gene Length505
Protein NamesAcid-sensing ion channel 5 (ASIC5) (Amiloride-sensitive cation channel 5) (Human intestine Na(+) channel) (HINaC)
Target NameNA
Target TypeNA
Gene Age987 ( ENSG00000256394 )
3 ( ENSG00000262505 )
Evolutionary StageEumetazoa
AlphaFoldDBQ9NY37
Gene CardASIC5
Uniprot IDQ9NY37
PfamPF00858
In ASDno
Allosteric Predictionno (-0.374823884)
Ortholog in AnimalsAlpaca_ ASIC5 ( ortholog_one2one )
Dog_ ASIC5 ( ortholog_one2one )
GuineaPig_ ASIC5 ( ortholog_one2one )
Macaque_ ASIC5 ( ortholog_one2one )
Mouse_ Asic5 ( ortholog_one2one )
Pig_ ASIC5 ( ortholog_one2one )
Rat_ Asic5 ( ortholog_one2one )
Rabbit_ ASIC5 ( ortholog_one2one )
OhnologsNA
ParalogsASIC1, SCNN1B, SCNN1G, ASIC4, SCNN1A, SCNN1D, ASIC2, ASIC3
TissueNA
Tissue SpecificityDetected in small intestine, duodenum and jejunum. Detected at very low levels in testis and rectum. {ECO:0000269|PubMed:10767424}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Cell membrane {ECO:0000269|PubMed:10767424};
Multi-pass membrane protein {ECO:0000269|PubMed:10767424}.
Mouse PG classificationNA
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