| Gene Information | |
|---|---|
| Gene Name | ASCL4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 172 |
| Protein Names | Achaete-scute homolog 4 (ASH-4) (hASH4) (Achaete-scute-like protein 4) (Class A basic helix-loop-helix protein 44) (bHLHa44) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000187855 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q6XD76 |
| Gene Card | ASCL4 |
| Uniprot ID | Q6XD76 |
| Pfam | PF00010 |
| In ASD | no |
| Allosteric Prediction | no (-0.594247469) |
| Ortholog in Animals | Alpaca_ ASCL4 ( ortholog_one2one ) Macaque_ ASCL4 ( ortholog_one2one ) Mouse_ Ascl4 ( ortholog_one2one ) Pig_ ASCL4 ( ortholog_one2one ) Rat_ Ascl4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ASCL2, ASCL5, ASCL1, ASCL3 |
| Tissue | NA |
| Tissue Specificity | Expressed in skin. 7-fold higher expression in fetal skin than in adult skin. Weak expression also detected in fetal lung, aorta and brain, and in adult stomach, kidney, ovary and breast. {ECO:0000269|PubMed:15475265}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}. |
| Mouse PG classification | NA |
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