| Gene Information | |
|---|---|
| Gene Name | ASCL2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 193 |
| Protein Names | Achaete-scute homolog 2 (ASH-2) (hASH2) (Class A basic helix-loop-helix protein 45) (bHLHa45) (Mash2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000183734 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q99929 |
| Gene Card | ASCL2 |
| Uniprot ID | Q99929 |
| Pfam | PF00010 |
| In ASD | no |
| Allosteric Prediction | no (-1.175490731) |
| Ortholog in Animals | Alpaca_ ASCL2 ( ortholog_one2one ) Dog_ ASCL2 ( ortholog_one2one ) GuineaPig_ ASCL2 ( ortholog_one2one ) Macaque_ ASCL2 ( ortholog_one2one ) Mouse_ Ascl2 ( ortholog_one2one ) Pig_ ASCL2 ( ortholog_one2one ) Rat_ Ascl2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ASCL4, ASCL5, ASCL1, ASCL3 |
| Tissue | NA |
| Tissue Specificity | Expressed specifically in the extravillous trophoblasts of the developing placenta. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981, ECO:0000269|PubMed:11440538}. |
| Mouse PG classification | NA |
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