| Gene Information | |
|---|---|
| Gene Name | APOL3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 402 |
| Protein Names | Apolipoprotein L3 (Apolipoprotein L-III) (ApoL-III) (TNF-inducible protein CG12-1) (CG12_1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 18 ( ENSG00000128284 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | O95236 |
| Gene Card | APOL3 |
| Uniprot ID | O95236 |
| Pfam | PF05461 |
| In ASD | no |
| Allosteric Prediction | no (-0.889265073) |
| Ortholog in Animals | Alpaca_ APOL3 ( ortholog_one2one ) Mouse_ Apol7a ( ortholog_many2many ) Mouse_ Apol7c ( ortholog_many2many ) Mouse_ Apol11a ( ortholog_many2many ) Mouse_ Apol8 ( ortholog_many2many ) Mouse_ Apol7e ( ortholog_many2many ) Mouse_ Apol7b ( ortholog_many2many ) Mouse_ Apol11b ( ortholog_many2many ) Mouse_ Apol10a ( ortholog_many2many ) Mouse_ Apol9a ( ortholog_many2many ) Mouse_ Apol9b ( ortholog_many2many ) Mouse_ Apol10b ( ortholog_many2many ) Rat_ Apol3 ( ortholog_many2many ) Rat_ AABR07058464.1 ( ortholog_many2many ) Rat_ AABR07058479.1 ( ortholog_many2many ) Rat_ Apol2 ( ortholog_many2many ) Rat_ RGD1309808 ( ortholog_many2many ) Rat_ Apol9a ( ortholog_many2many ) |
| Ohnologs | NA |
| Paralogs | APOL4, APOL1, APOL2, APOL6, APOL5, APOLD1 |
| Tissue | NA |
| Tissue Specificity | Widely expressed; the highest levels are in prostate, lung and placenta; also detected in kidney, bone marrow, spleen, thymus, spinal cord, adrenal gland, salivary gland, trachea and mammary gland; levels are low in brain, heart, fetal liver, pancreas and testis. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs132653 rs6000152 |
| Subcellular location [CC] | Cytoplasm {ECO:0000305}. |
| Mouse PG classification | NA |
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