| Gene Information | |
|---|---|
| Gene Name | ASAP3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 903 |
| Protein Names | Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 (Development and differentiation-enhancing factor-like 1) (Protein up-regulated in liver cancer 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000088280 ) 3 ( ENSG00000282854 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8TDY4 |
| Gene Card | ASAP3 |
| Uniprot ID | Q8TDY4 |
| Pfam | PF12796; PF01412; PF00169 |
| In ASD | no |
| Allosteric Prediction | no (-0.99990676) |
| Ortholog in Animals | Alpaca_ ASAP3 ( ortholog_one2one ) Dog_ ASAP3 ( ortholog_one2one ) GuineaPig_ ASAP3 ( ortholog_one2one ) Macaque_ ASAP3 ( ortholog_one2one ) Mouse_ Asap3 ( ortholog_one2one ) Pig_ ASAP3 ( ortholog_one2one ) Rat_ Asap3 ( ortholog_one2one ) Rabbit_ ASAP3 ( ortholog_one2one ) |
| Ohnologs | ASAP2, ASAP1 |
| Paralogs | ASAP2, ASAP1, ACAP3, ARAP2, GIT1, ARAP3, AGFG1, ADAP1, SMAP1, AGAP1, ACAP2, AGAP3, AGAP4, AGAP6, AGAP9, AGAP5, ARFGAP1, APPL1, ARFGAP2, ARAP1, AGFG2, APPL2, ARFGAP3, GIT2, ADAP2, SMAP2, AGAP2, ACAP1 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in primary hepatocarcinoma. Detected in lung, liver and blood leukocytes. {ECO:0000269|PubMed:14654939}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2B0O (X-ray 2.06A ) 3LVQ (X-ray 3.38A ) 3LVR (X-ray 3.38A ) |
| DBSNP | rs16828486 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:14654939}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |